Description

5-Bromo-2-(Chloromethyl)Pyrimidine is a versatile and high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization in medicinal chemistry.
• Material Science: Potential monomer or precursor for the synthesis of specialized polymers and organic electronic materials.
• Bioconjugation & Probe Development: The reactive chloromethyl group allows for attachment to biomolecules, useful in creating diagnostic probes or targeted drug conjugates.

Basic Information

Product Name	5-Bromo-2-(Chloromethyl)Pyrimidine
CAS No.	944900-08-7
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	2-(Chloromethyl)-5-bromopyrimidine; 5-Bromo-2-chloromethylpyrimidine; Pyrimidine, 5-bromo-2-(chloromethyl)-; 5-Bromo-2-(chloromethyl)pyrimidine; 944900-08-7; 5-Br-2-Cl-CH2-Pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Chloromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.