Description

5-Trifluoromethyl-Pyrimidine-2-Carbaldehyde is a high-purity, versatile trifluoromethylated pyrimidine building block essential for advanced organic synthesis. This compound is particularly valued for introducing the trifluoromethyl group and aldehyde functionality into target molecules, enabling the development of compounds with enhanced metabolic stability and lipophilicity. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics, liquid crystals, and advanced polymers.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the synthesis of molecular probes and labeled compounds.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis services targeting complex, fluorinated molecular architectures.

Basic Information

Product Name	5-Trifluoromethyl-Pyrimidine-2-Carbaldehyde
CAS No.	944900-00-9
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	2-Pyrimidinecarboxaldehyde, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)pyrimidine-2-carboxaldehyde; 5-Trifluoromethyl-2-pyrimidinecarbaldehyde; 5-Trifluoromethyl-2-formylpyrimidine; 5-Trifluoromethylpyrimidine-2-carboxaldehyde; 944900-00-9; 5-Trifluoromethyl-2-pyrimidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Trifluoromethyl-Pyrimidine-2-Carbaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your research and production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere if opened, to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.