Description

trans-4-Fluorocinnamaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily sought by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in synthesizing active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions like Suzuki-Miyaura and Heck couplings for creating biaryl structures.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex aromatic molecules for high-value fragrance compositions.
• Academic & R&D: A versatile reagent in medicinal chemistry and material science research for exploring structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	trans-4-Fluorocinnamaldehyde
CAS No.	944899-61-0
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	(E)-3-(4-Fluorophenyl)acrylaldehyde; (E)-4-Fluorocinnamaldehyde; trans-3-(4-Fluorophenyl)-2-propenal; p-Fluorocinnamaldehyde; (E)-3-(4-Fluorophenyl)prop-2-enal; 4-Fluorocinnamaldehyde (trans); (2E)-3-(4-Fluorophenyl)prop-2-enal
EINECS	Contact for details

Quality Control

Our trans-4-Fluorocinnamaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.