Description

Ethyl 2-(Chloromethyl)Pyrimidine-4-Carboxylate is a high-value pyrimidine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and an ester functionality, makes it an essential precursor for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various pyrimidine-based drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of specialty polymers and organic electronic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	Ethyl 2-(Chloromethyl)Pyrimidine-4-Carboxylate
CAS No.	944899-56-3
Molecular Formula	C8H9ClN2O2
Molecular Weight	200.62 g/mol
Synonyms	Ethyl 2-(chloromethyl)-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 2-(chloromethyl)-, ethyl ester; 2-(Chloromethyl)pyrimidine-4-carboxylic acid ethyl ester; Ethyl 2-(chloromethyl)pyrimidine-4-carboxylate; 944899-56-3; Ethyl (2-chloromethyl)pyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Chloromethyl)Pyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.