Description

5,6-Difluoro-1H-Indazole is a high-value fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in the strategic incorporation of fluorine atoms, which can dramatically enhance the metabolic stability, bioavailability, and binding affinity of target molecules. This compound is primarily needed by R&D scientists and process chemists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new generations of herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for advanced organic electronic materials and functional polymers.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fluorine Chemistry: A valuable substrate for further functionalization in organofluorine chemistry research.

Basic Information

Product Name	5,6-Difluoro-1H-Indazole
CAS No.	944898-96-8
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	1H-Indazole, 5,6-difluoro-; 5,6-Difluoroindazole; 5,6-Difluoro-1H-indazole; 944898-96-8; 5,6-Difluorindazol; 5,6-Difluoro-1H-benzo[d]imidazole (incorrect but common misnomer); DFI (abbreviation)
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-1H-Indazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.