Description

3-Trifluoromethoxyphenylacetaldehyde is a high-value fluorinated aromatic aldehyde building block. This compound is essential for introducing the unique trifluoromethoxy-phenyl moiety into complex molecular architectures, significantly altering physicochemical properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its structural features can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group can improve lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and material science.
• Fluorinated Liquid Crystal Research: Employed in the synthesis of fluorinated mesogens for advanced display technologies.
• Organic Electronic Materials: A building block for electron-deficient units in organic semiconductors and OLED materials.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke research projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	3-Trifluoromethoxyphenylacetaldehyde
CAS No.	944898-37-7
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-(Trifluoromethoxy)phenylacetaldehyde; 2-[3-(Trifluoromethoxy)phenyl]acetaldehyde; m-Trifluoromethoxyphenylacetaldehyde; 3-Trifluoromethoxybenzeneacetaldehyde; α-Oxo-2-[3-(trifluoromethoxy)phenyl]ethane; (3-Trifluoromethoxyphenyl)acetaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Trifluoromethoxyphenylacetaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by GC, HPLC, and NMR is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.