Description

Benzamide, 3-[[4-[(5-Hydroxy-2-Methylphenyl)Amino]-2-Pyrimidinyl]Amino]- is a high-purity, synthetically derived organic compound featuring a benzamide core substituted with an aminopyrimidine moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a critical building block in medicinal chemistry research. It is primarily sought after by R&D and manufacturing teams in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents. The compound's structure suggests potential utility in targeting specific biological pathways, making it essential for early-stage drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) for potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold or precursor in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating enzyme inhibition or receptor binding mechanisms.
• Organic Synthesis: Acts as a versatile intermediate for constructing more complex heterocyclic compounds and fine chemicals.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Benzamide, 3-[[4-[(5-Hydroxy-2-Methylphenyl)Amino]-2-Pyrimidinyl]Amino]-
CAS No.	944795-06-6
Molecular Formula	C18H17N5O2
Molecular Weight	335.36 g/mol
Synonyms	3-({4-[(5-Hydroxy-2-methylphenyl)amino]pyrimidin-2-yl}amino)benzamide; N-[3-({4-[(5-Hydroxy-2-methylphenyl)amino]pyrimidin-2-yl}amino)phenyl]formamide (tautomer); 3-[[4-[(5-Hydroxy-o-tolyl)amino]-2-pyrimidinyl]amino]benzamide; Benzamide, N-[3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]phenyl]-; 944795-06-6; UNII-8V4Y1W2G5Q
EINECS	Contact for details

Quality Control

Our production of Benzamide, 3-[[4-[(5-Hydroxy-2-Methylphenyl)Amino]-2-Pyrimidinyl]Amino]- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, handling under inert atmosphere and desiccated conditions is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.