Description

4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), kinase inhibitors, and other novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that leverage its heterocyclic core for biological activity.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study enzyme function and cellular signaling pathways.
• Material Science: Potential building block for organic electronic materials and advanced polymers due to its fused aromatic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester
CAS No.	944709-69-7
Molecular Formula	C9H6ClN3O2
Molecular Weight	223.62 g/mol
Synonyms	Methyl 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid methyl ester; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-methyl carboxylate; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, methyl ester; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate, methyl; 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid methyl ester (CAS 944709-69-7)
EINECS	Contact for details

Quality Control

Our 4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.