Description

2-Fluoro-1H-Indole is a fluorinated derivative of the indole heterocycle, a privileged scaffold in medicinal chemistry. This compound matters as a versatile and valuable building block for the synthesis of novel pharmaceutical intermediates and agrochemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used to develop new fluorinated pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science: Serves as a monomer or functional group for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Employed as a probe or tag in biochemical research to study protein-ligand interactions and enzyme mechanisms.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Fluoro-1H-Indole
CAS No.	944347-13-1
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	2-Fluoroindole; 2-Fluoro-1H-indole; 1H-Indole, 2-fluoro-; 2-F-Indole; 2-Fluorindol; 2-Fluoro-1H-benzo[b]pyrrole
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.