Description

(tert-Butoxy)Carbonyl Thr((9H-Fluoren-9-Yl)Methoxy]Carbonyl Gln(Trt))-Oh is a sophisticated, multi-protected peptide building block designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity, sequence-specific intermediates to construct complex peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and CROs engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected amino acid derivative for the sequential assembly of peptide chains on resin.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: Acts as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Biochemical Reagent Production: Integral for synthesizing custom peptides used as substrates, standards, or probes in enzymatic assays and diagnostic kits.
• Academic Research: Supports fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Item	Details
Product Name	(tert-Butoxy)Carbonyl Thr((9H-Fluoren-9-Yl)Methoxy]Carbonyl Gln(Trt))-Oh
CAS No.	944283-36-7
Molecular Formula	C55H61N3O9
Molecular Weight	908.10 g/mol
Synonyms	Boc-Thr(Fmoc-Gln(Trt))-OH; Fmoc-Gln(Trt)-Thr(Boc)-OH; Boc-L-Threonine(Fmoc-L-glutamine(Trt))-OH; N-α-Boc-N-γ-Fmoc-L-glutamine(Trt)-L-threonine; (2S)-2-[[(2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-5-oxo-5-(triphenylmethoxy)pentanoyl]amino]-3-[(2-methylpropan-2-yl)oxycarbonyloxy]propanoic acid; Protected Threonine-Glutamine Dipeptide; SPPS Building Block for Thr-Gln sequence.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for peptide synthesis. Every batch is characterized by advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, chiral integrity, and spectroscopic data are available upon request. We adhere to GMP-grade handling procedures for high-value research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or in a controlled atmosphere (e.g., nitrogen or argon) when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Chiral Purity (HPLC)	≥ 99.0% (D-isomer ≤ 1.0%)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.