Description

(tert-Butoxy)Carbonyl Ser((9H-Fluoren-9-Yl)Methoxy]Carbonyl Leu)-Oh is a specialized, protected dipeptide building block used in solid-phase peptide synthesis (SPPS). This compound matters for its role in constructing complex peptide sequences with high precision, offering orthogonal protection for the serine side chain and the N-terminus. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediates: Critical building block for the synthesis of novel therapeutic peptide candidates targeting various diseases.
• Peptide Research & Development: Used in academic and industrial R&D labs for constructing custom peptide sequences with specific side-chain protection.
• Bioconjugation: Serves as a precursor for creating peptide-based conjugates used in drug delivery systems or diagnostic probes.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening to discover new bioactive molecules.
• Process Development: Employed in scaling up and optimizing synthetic routes for peptide-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(tert-Butoxy)Carbonyl Ser((9H-Fluoren-9-Yl)Methoxy]Carbonyl Leu)-Oh
CAS No.	944283-09-4
Molecular Formula	C30H38N2O8
Molecular Weight	554.64 g/mol
Synonyms	Boc-Ser(Fmoc)-Leu-OH; Fmoc-Ser(tBu)-Leu-OH; Boc-L-Ser(Fmoc-L-Leu)-OH; (2S)-2-[[(2S)-3-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-4-methylpentanoic acid; Nα-Boc-Nγ-Fmoc-L-seryl-L-leucine; Boc-Ser(Fmoc)-Leu; Protected Ser-Leu dipeptide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, chiral purity, and other critical parameters are available upon request. We adhere to cGMP guidelines for the production of high-value pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.