Description

Methyl 2,6-Dibromo-5-Chloropyrimidine-4-Carboxylate is a high-purity, multi-functional halogenated pyrimidine building block essential for advanced organic synthesis. This compound is valued for its reactive halogen sites, which enable precise derivatization and the construction of complex heterocyclic scaffolds. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its halogenated pyrimidine core.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential intermediate for the development of specialty chemicals, dyes, and functional materials requiring halogenated heterocycles.

Basic Information

Product Name	Methyl 2,6-Dibromo-5-Chloropyrimidine-4-Carboxylate
CAS No.	944128-95-4
Molecular Formula	C7H3Br2ClN2O2
Molecular Weight	354.37 g/mol
Synonyms	Methyl 5-Chloro-2,6-dibromopyrimidine-4-carboxylate; 2,6-Dibromo-5-chloropyrimidine-4-carboxylic acid methyl ester; 5-Chloro-2,6-dibromo-4-pyrimidinecarboxylic acid methyl ester; Methyl 5-chloro-2,6-dibromo-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 2,6-dibromo-5-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2,6-Dibromo-5-Chloropyrimidine-4-Carboxylate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and scale-up with specifications that meet the rigorous demands of cGMP and ISO-guided environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.