Description

4-Amino-2-Chloro-5-Pyrimidinol is a versatile pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering distinct sites for nucleophilic substitution and further functionalization, which is critical for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, antiviral drugs, and kinase inhibitors.
• Agrochemical Synthesis: Serves as a core scaffold for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Used as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized heterocyclic dyes and optical brighteners.
• Material Science: Potential monomer or modifier in the synthesis of advanced polymers and organic electronic materials.

Basic Information

Item	Detail
Product Name	4-Amino-2-Chloro-5-Pyrimidinol
CAS No.	943995-31-1
Molecular Formula	C4H4ClN3O
Molecular Weight	145.55 g/mol
Synonyms	2-Chloro-4-amino-5-hydroxypyrimidine; 5-Hydroxy-2-chloro-4-aminopyrimidine; 4-Amino-2-chloro-5-hydroxypyrimidine; 4-Amino-2-chloropyrimidin-5-ol; 2-Chloro-4-aminopyrimidin-5-ol; 4-Amino-2-chloro-5-pyridinol (common misnomer); A2C5P (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-2-Chloro-5-Pyrimidinol is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, to ensure consistent quality and traceability for your R&D and production needs. Our standard grade meets typical research and intermediate synthesis requirements, with custom purity grades available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.