Description

2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine is a high-purity heterocyclic organic compound featuring a pyrimidine core substituted with an amine and a methylpiperazine group. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector. The compound is essential for constructing complex molecules targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies during drug discovery campaigns.
• Chemical Biology Probe Development: Serves as a core scaffold for creating tool compounds to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for novel heterocyclic chemistry methodology development and bioorganic studies.

Basic Information

Product Name	2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine
CAS No.	943757-74-2
Molecular Formula	C9H14N6
Molecular Weight	206.25 g/mol
Synonyms	5-Amino-2-(4-methyl-1-piperazinyl)pyrimidine; 2-(4-Methylpiperazin-1-yl)pyrimidin-5-ylamine; 2-(4-Methyl-1-piperazinyl)-5-pyrimidinamine; 5-Pyrimidinamine, 2-(4-methyl-1-piperazinyl)-; 943757-74-2; 2-(4-Methylpiperazin-1-Yl)Pyrimidin-5-Amine
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.