Description

2-Amino-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its crucial role as a versatile scaffold in the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral therapeutic areas. Pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists need this precise chemical to drive forward their discovery pipelines and create next-generation products.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors and other targeted cancer therapies.
• Agrochemical Research: Used in developing novel herbicides and fungicides with specific modes of action.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme mechanisms and cellular pathways.
• Material Science: Acts as a building block for creating specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and process development.
• Library Synthesis: Utilized for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Amino-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	943736-58-1
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	4-Chloro-2-amino-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidin-2-amine, 4-chloro-; 2-Amino-4-chloro-7-azaindole; 4-Chloro-7-azaindol-2-amine; 4-Chloro-2-aminopyrrolopyrimidine; 2-Amino-4-chloropyrrolo[3,2-d]pyrimidine; 4-Chloro-2-aminopyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.