Description

2-C-Methyl-3,5-Di-o-(4-Methylbenzoyl)-D-Ribofuranose CAS NO 943638-20-8 is a key protected ribofuranose derivative, serving as a critical chiral intermediate in the synthesis of complex nucleoside analogs and other biologically active molecules. Its value lies in providing a strategically functionalized sugar scaffold that enables precise stereochemical control in downstream pharmaceutical manufacturing. This high-purity intermediate is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those developing antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Pro-drug Synthesis: Used in the development of pro-drug forms of nucleoside analogs to enhance bioavailability and therapeutic efficacy.
• Antiviral Research: Serves as a precursor in the research and development of compounds targeting RNA viruses, including hepatitis C virus (HCV).
• Chemical Biology: Employed in the synthesis of labeled or modified nucleosides for mechanistic studies and diagnostic applications.
• Fine Chemical Synthesis: Acts as a chiral synthon for constructing complex natural products and specialty chemicals requiring specific sugar motifs.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.

Basic Information

Product Name	2-C-Methyl-3,5-Di-o-(4-Methylbenzoyl)-D-Ribofuranose
CAS No.	943638-20-8
Molecular Formula	C23H24O7
Molecular Weight	412.43 g/mol
Synonyms	2-C-Methyl-3,5-di-O-p-toluoyl-D-ribofuranose; 2-C-Methyl-3,5-di-O-(4-methylbenzoyl)-D-ribofuranose; 2-C-Methyl-3,5-bis-O-(4-methylbenzoyl)-D-ribofuranose; 2-C-Methyl-D-ribofuranose 3,5-bis(4-methylbenzoate); 2-C-Methyl-3,5-di-p-toluoyl-D-ribofuranose; 2-C-Methyl-3,5-di-O-(p-toluoyl)-D-ribofuranose; 2-C-Methyl-3,5-di-O-(4-methylbenzoyl)-alpha/β-D-ribofuranose mixture
EINECS	Contact for details

Quality Control

Our 2-C-Methyl-3,5-Di-o-(4-Methylbenzoyl)-D-Ribofuranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support customer requirements for GMP-grade material and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.