Description

6-Bromo-7-Methylquinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is of significant commercial importance for its role in the synthesis of complex bioactive molecules, particularly kinase inhibitors used in targeted cancer therapies. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel quinazoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted therapeutic agents for oncology research.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and signal transduction pathways in drug discovery.
• Agrochemical Research: Serves as a building block for developing new herbicides and fungicides with novel modes of action.
• Material Science: Investigated as a monomer or additive for creating specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-Bromo-7-Methylquinazolin-4(3H)-One
CAS No.	943605-85-4
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	6-Bromo-7-methyl-3,4-dihydroquinazolin-4-one; 6-Bromo-7-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 6-bromo-7-methyl-; 943605-85-4; 6-Bromo-7-methylquinazolin-4-ol; 7-Methyl-6-bromoquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Methylquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.