Description

4-Chloro-8-Iodo-2,7-Dimethylquinazoline is a high-value, multi-functional halogenated quinazoline derivative. This compound serves as a critical synthetic intermediate and building block in advanced organic synthesis, prized for its unique halogen substitution pattern. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive quinazoline core.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry and biochemical research.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to construct more complex heterocyclic systems.

Basic Information

Product Name	4-Chloro-8-Iodo-2,7-Dimethylquinazoline
CAS No.	943603-29-0
Molecular Formula	C10H8ClIN2
Molecular Weight	318.54 g/mol
Synonyms	4-Chloro-8-iodo-2,7-dimethylquinazoline; 2,7-Dimethyl-4-chloro-8-iodoquinazoline; Quinazoline, 4-chloro-8-iodo-2,7-dimethyl-; 943603-29-0; 4-Chloro-8-iodo-2,7-dimethyl-quinazoline; 8-Iodo-4-chloro-2,7-dimethylquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Iodo-2,7-Dimethylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.