Description

Ethyl2,2-Difluoro-2-(Quinolin-6-Yl)Acetate is a high-value fluorinated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of fluorine atoms and the quinoline scaffold, enabling the development of novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients, particularly in medicinal chemistry programs targeting kinase inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorinated quinoline structure can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for creating specialized fluorinated organic compounds used in advanced materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated intermediates.
• Academic & Industrial R&D: Essential for exploratory chemistry in university laboratories and corporate R&D centers focused on fluorine chemistry and heterocyclic compounds.

Basic Information

Product Name	Ethyl2,2-Difluoro-2-(Quinolin-6-Yl)Acetate
CAS No.	943541-40-0
Molecular Formula	C₁₃H₁₁F₂NO₂
Molecular Weight	251.23 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(6-quinolyl)acetate; 2,2-Difluoro-2-(quinolin-6-yl)acetic Acid Ethyl Ester; 6-Quinolineacetic Acid, 2,2-Difluoro-, Ethyl Ester; Acetic Acid, 2,2-Difluoro-2-(6-quinolinyl)-, Ethyl Ester; Ethyl α,α-Difluoro-6-quinolineacetate; 943541-40-0; Ethyl 2,2-Difluoro-2-(6-quinolyl)ethanoate
EINECS	Contact for details

Quality Control

Our Ethyl2,2-Difluoro-2-(Quinolin-6-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.