Description

3-[(2-Chloropyrimidin-4-Yl)Oxy]Aniline is a high-purity, specialized organic intermediate featuring a chloropyrimidine core linked to an aniline derivative via an ether bond. This unique bifunctional structure makes it a critical building block for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Chemical Synthesis Building Block: Serves as a versatile reagent for constructing complex molecular architectures in medicinal and process chemistry.
• Material Science Research: Potential monomer or precursor for creating functional polymers and advanced organic materials.
• Academic & Contract Research: Essential for exploratory chemistry in university labs and CROs (Contract Research Organizations).

Basic Information

Product Name	3-[(2-Chloropyrimidin-4-Yl)Oxy]Aniline
CAS No.	943314-62-3
Molecular Formula	C10H8ClN3O
Molecular Weight	221.64 g/mol
Synonyms	4-[(2-Chloropyrimidin-4-yl)oxy]benzenamine; 3-Amino-1-(2-chloropyrimidin-4-yl)oxybenzene; 1-(2-Chloro-4-pyrimidinyl)oxy-3-aminobenzene; Benzenamine, 4-[(2-chloro-4-pyrimidinyl)oxy]-; 3-[(2-Chloro-4-pyrimidinyl)oxy]aniline; 4-(3-Aminophenoxy)-2-chloropyrimidine; 2-Chloro-4-(3-aminophenoxy)pyrimidine
EINECS	Contact for details

Quality Control

Our 3-[(2-Chloropyrimidin-4-Yl)Oxy]Aniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support development under cGMP (current Good Manufacturing Practice) guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.