Description

tert-Butyl 4-(6-Cyanopyrimidin-4-Yloxy)Phenylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine and carbamate functional groups. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. Pharmaceutical manufacturers and R&D organizations need this material for its precise structural features that enable the construction of targeted therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Preclinical & Clinical Research: Used in medicinal chemistry for the discovery and optimization of novel drug candidates.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization due to its reactive cyanopyrimidine and protected carbamate groups.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations specializing in the custom synthesis of complex organic molecules for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and biochemical pathways.

Basic Information

Product Name	tert-Butyl 4-(6-Cyanopyrimidin-4-Yloxy)Phenylcarbamate
CAS No.	943313-34-6
Molecular Formula	C16H16N4O3
Molecular Weight	312.33 g/mol
Synonyms	tert-Butyl N-[4-[(6-cyanopyrimidin-4-yl)oxy]phenyl]carbamate; 4-[(6-Cyanopyrimidin-4-yl)oxy]phenyl Carbamic Acid tert-Butyl Ester; BOC-4-(6-Cyanopyrimidin-4-yloxy)aniline; 943313-34-6; 4-(6-Cyanopyrimidin-4-yloxy)phenylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Cyanopyrimidin-4-Yloxy)Phenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.