Description

Methyl 1-(4-Fluorophenyl)Cyclopropanecarboxylate is a high-value fluorinated cyclopropane derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a cyclopropane ring and a fluorinated aromatic system, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, where its scaffold offers significant potential for bioactivity modulation.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage the fluorophenyl group for enhanced efficacy and environmental profile.
• Material Science Research: Used in the creation of specialty monomers and polymers, where the cyclopropane ring can impart unique rigidity and stability to the final material.
• Ligand and Catalyst Development: Serves as a scaffold for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated cyclopropane motifs.

Basic Information

Product Name	Methyl 1-(4-Fluorophenyl)Cyclopropanecarboxylate
CAS No.	943111-83-9
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	Methyl 1-(4-fluorophenyl)cyclopropanecarboxylate; 1-(4-Fluorophenyl)cyclopropanecarboxylic acid methyl ester; Methyl 1-(p-fluorophenyl)cyclopropanecarboxylate; 4-Fluorophenyl cyclopropanecarboxylate methyl ester; Cyclopropanecarboxylic acid, 1-(4-fluorophenyl)-, methyl ester; Methyl (1-(4-fluorophenyl)cyclopropyl)carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1-(4-Fluorophenyl)Cyclopropanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.