Description

6-Chloro-5-Fluoro-2-Methylpyrimidin-4-Amine is a high-purity, multi-functional pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which provides specific reactivity for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands, or organic electronic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	6-Chloro-5-Fluoro-2-Methylpyrimidin-4-Amine
CAS No.	943006-45-9
Molecular Formula	C5H5ClFN3
Molecular Weight	161.56 g/mol
Synonyms	4-Amino-6-chloro-5-fluoro-2-methylpyrimidine; 5-Fluoro-6-chloro-2-methylpyrimidin-4-amine; 2-Methyl-6-chloro-5-fluoropyrimidin-4-amine; 6-Chloro-5-fluoro-2-methyl-4-pyrimidinamine; 4-Pyrimidinamine, 6-chloro-5-fluoro-2-methyl-; 943006-45-9
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Fluoro-2-Methylpyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.