Description

Phenol, 2-Fluoro-6-(Trifluoromethoxy)- is a high-value fluorinated phenol derivative, distinguished by its unique trifluoromethoxy substituent. This compound serves as a critical advanced pharmaceutical intermediate and agrochemical building block, enabling the synthesis of novel active ingredients with enhanced properties. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine chemistry for improved bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the trifluoromethoxy group confers improved lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display and lighting applications.
• Polymer Modification: Monomer or additive for creating specialty polymers with specific thermal and chemical resistance profiles.
• Organic Synthesis Reagent: Versatile starting material or coupling partner in cross-coupling reactions and nucleophilic aromatic substitution.
• Chemical Research & Development: Essential for academic and industrial research exploring new fluorinated compounds and their properties.

Basic Information

Product Name	Phenol, 2-Fluoro-6-(Trifluoromethoxy)-
CAS No.	942618-24-8
Molecular Formula	C7H4F4O2
Molecular Weight	196.10 g/mol
Synonyms	2-Fluoro-6-(trifluoromethoxy)phenol; 6-Fluoro-2-(trifluoromethoxy)phenol; 1-Fluoro-3-hydroxy-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)-6-fluorophenol; Phenol, o-fluoro-m-(trifluoromethoxy)-; FTOPh-OH; 2-F-6-TFMP
EINECS	Contact for details

Quality Control

Our Phenol, 2-Fluoro-6-(Trifluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation by NMR, IR, and GC-MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.