Description

4-Ethoxy-3,5-Difluoroaniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the aniline group combined with the electronic effects of the fluorine and ethoxy substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antibiotic research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines used in electronic display technologies.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polyimides and high-performance polymers.
• Dyestuff & Pigment Intermediate: Employed in the creation of specialized, light-fast dyes and colorants.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions for complex molecule assembly.

Basic Information

Product Name	4-Ethoxy-3,5-Difluoroaniline
CAS No.	942615-19-2
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	3,5-Difluoro-4-ethoxyaniline; 4-Amino-2,6-difluorophenetole; 2,6-Difluoro-4-ethoxyaniline; 4-Ethoxy-3,5-difluorobenzenamine; Benzenamine, 3,5-difluoro-4-ethoxy-; 942615-19-2; 4-Ethoxy-3,5-difluoro-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluoroaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, assay, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.