Description

3,5-Difluoro-4-isopropoxybenzenamine is a high-purity aromatic amine derivative, distinguished by its fluorine and isopropoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of complex active ingredients. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalytic systems in asymmetric synthesis.
• Fluorescent Probe Synthesis: Acts as a precursor for developing diagnostic imaging agents and biochemical sensors.
• Academic & Industrial R&D: A versatile reagent for exploratory chemistry in medicinal and synthetic organic chemistry programs.

Basic Information

Product Name	3,5-Difluoro-4-isopropoxybenzenamine
CAS No.	942615-18-1
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	3,5-Difluoro-4-isopropoxyaniline; 4-Isopropoxy-3,5-difluoroaniline; 3,5-Difluoro-4-(1-methylethoxy)benzenamine; Benzenamine, 3,5-difluoro-4-(1-methylethoxy)-; 942615-18-1; 3,5-Difluoro-4-isopropoxy-phenylamine; 3,5-Difluoro-4-(propan-2-yloxy)aniline
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-isopropoxybenzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.