Description

(E)-n-(4-((tert-Butyldimethylsilyl)Oxy)Benzylidene)-4-Fluoroaniline (Wxc03546) is a high-purity, advanced pharmaceutical intermediate featuring a benzylidene aniline core protected by a tert-butyldimethylsilyl (TBDMS) group. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting a range of therapeutic areas. Its defined structure and purity make it an essential building block for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities, particularly those incorporating fluorinated aromatic systems.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing Schiff base ligands or more complex heterocyclic frameworks in academic and industrial R&D.
• Material Science Research: Potential use in the development of specialty chemicals, advanced polymers, or functional materials due to its specific molecular architecture.

Basic Information

Product Name	(E)-n-(4-((tert-Butyldimethylsilyl)Oxy)Benzylidene)-4-Fluoroaniline (Wxc03546)
CAS No.	942485-61-2
Molecular Formula	C19H24FNOSi
Molecular Weight	329.49 g/mol
Synonyms	(E)-N-(4-((tert-Butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline; 4-Fluoro-N-[(E)-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenylmethylene]benzenamine; WXC-03546; Wxc03546; 4-Fluoro-N-[(E)-4-[(tert-butyldimethylsilyl)oxy]benzylidene]aniline; (E)-4-Fluoro-N-(4-((tert-butyldimethylsilyl)oxy)benzylidene)aniline; N-(4-((tert-Butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline
EINECS	Contact for details

Quality Control

Our (E)-n-(4-((tert-Butyldimethylsilyl)Oxy)Benzylidene)-4-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.