Description

4'-Fluoro-3'-Trifluoromethyl-Biphenyl-4-Ylamine is a high-purity, functionalized biphenyl amine derivative. This compound is a critical advanced pharmaceutical intermediate (API) valued for its role in constructing complex molecular architectures. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine and trifluoromethyl groups.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials, host materials, and other functional components in display and lighting technologies.
• Polymer Science: Incorporated as a monomer or additive to create specialty polymers with enhanced thermal stability, chemical resistance, or specific optical properties.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a sophisticated amine component in cross-coupling reactions and other catalytic processes.
• Life Science Research: Utilized as a biochemical tool and probe in academic and industrial research for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	4'-Fluoro-3'-Trifluoromethyl-Biphenyl-4-Ylamine
CAS No.	942474-96-6
Molecular Formula	C13H9F4N
Molecular Weight	255.21 g/mol
Synonyms	4'-Fluoro-3'-(trifluoromethyl)[1,1'-biphenyl]-4-amine; 4-Amino-4'-fluoro-3'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-amine, 4'-fluoro-3'-(trifluoromethyl)-; 4'-Fluoro-3'-trifluoromethylbiphenyl-4-ylamine; 4-(4-Fluoro-3-(trifluoromethyl)phenyl)aniline
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3'-Trifluoromethyl-Biphenyl-4-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP, ISO, and REACH standards as required for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.