Description

2-Methylsulfonyl-5-Trifluoromethylbenzaldehyde is a high-purity aromatic aldehyde building block featuring both a trifluoromethyl and a methylsulfonyl substituent. This compound is valued for its unique electronic properties, making it a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the trifluoromethyl group improves lipophilicity and bioavailability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and signal transduction pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Methylsulfonyl-5-Trifluoromethylbenzaldehyde
CAS No.	942474-52-4
Molecular Formula	C9H7F3O3S
Molecular Weight	252.21 g/mol
Synonyms	5-(Trifluoromethyl)-2-(methylsulfonyl)benzaldehyde; 2-(Methylsulfonyl)-5-(trifluoromethyl)benzaldehyde; 2-Methanesulfonyl-5-trifluoromethylbenzaldehyde; α-Oxo-2-(methylsulfonyl)-5-(trifluoromethyl)benzenemethanol; Benzaldehyde, 2-(methylsulfonyl)-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methylsulfonyl-5-Trifluoromethylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.