Description

6-Chloro-8-n-Morpholino-3-(2′,3′-Dioxypropyl)-Purine is a high-purity, functionalized purine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of novel pharmaceutical agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on kinase inhibitors, nucleotide analogs, and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Biochemical Research: Used as a modified nucleobase scaffold for studying enzyme-substrate interactions and signal transduction pathways.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and library synthesis.
• Nucleotide Analog Development: Employed in creating novel purine analogs for antiviral or anticancer research applications.
• Chemical Biology Probes: Functionalized for use in affinity purification, labeling, or as activity-based probes in proteomics.

Basic Information

Product Name	6-Chloro-8-n-Morpholino-3-(2′,3′-Dioxypropyl)-Purine
CAS No.	942357-79-1
Molecular Formula	C14H18ClN5O3
Molecular Weight	339.78 g/mol
Synonyms	6-Chloro-8-morpholino-3-(2,3-dihydroxypropyl)purine; 6-Chloro-8-morpholin-4-yl-3-(2,3-dihydroxypropyl)-7H-purine; 6-Chloro-8-(morpholin-4-yl)-3-(2,3-dihydroxypropyl)-1H-purine; 3-(2,3-Dihydroxypropyl)-6-chloro-8-morpholinopurine; 942357-79-1; Purine, 6-chloro-8-(4-morpholinyl)-3-(2,3-dihydroxypropyl)-; 6-Chloro-8-morpholino-3-(2,3-dihydroxypropyl)-9H-purine
EINECS	Contact for details

Quality Control

Our 6-Chloro-8-n-Morpholino-3-(2′,3′-Dioxypropyl)-Purine is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.