Description

5-Pyrimidinamine, 4-Iodo- is a halogenated pyrimidine derivative, a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic iodine substituent, which enables versatile cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic electronics and advanced materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	5-Pyrimidinamine, 4-Iodo-
CAS No.	942067-98-3
Molecular Formula	C4H4IN3
Molecular Weight	221.00 g/mol
Synonyms	4-Iodo-5-pyrimidinamine; 4-Iodopyrimidin-5-amine; 5-Amino-4-iodopyrimidine; 4-Iodo-5-aminopyrimidine; 4-Iodo-pyrimidin-5-ylamine; 5-Pyrimidinamine, 4-iodo-; 942067-98-3; 4-Iodo-5-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinamine, 4-Iodo- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.