Description

5-Bromo-4-Hydroxy-6-Trifluoromethylpyrimidine is a high-value, multi-functional heterocyclic building block. This compound is strategically important for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals due to its unique halogenated and trifluoromethylated structure. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides with enhanced activity and environmental profile.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	5-Bromo-4-Hydroxy-6-Trifluoromethylpyrimidine
CAS No.	942060-14-2
Molecular Formula	C5H2BrF3N2O
Molecular Weight	242.98 g/mol
Synonyms	4-Hydroxy-5-bromo-6-(trifluoromethyl)pyrimidine; 5-Bromo-6-(trifluoromethyl)pyrimidin-4-ol; 5-Bromo-4-hydroxy-6-(trifluoromethyl)pyrimidine; 942060-14-2; 4(1H)-Pyrimidinone, 5-bromo-6-(trifluoromethyl)-; 5-Bromo-6-trifluoromethyl-4-hydroxypyrimidine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 5-Bromo-4-Hydroxy-6-Trifluoromethylpyrimidine is analyzed using advanced techniques like HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system supports development from milligram to kilogram scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.