Description

1-(2-Hydroxyethyl)-6-Mercapto-1,5-Dihydro-4{H}-Pyrazolo[3,4-{D}]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazolopyrimidinone core. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of purine nucleoside analogue-based active pharmaceutical ingredients (APIs).
• Oncology Drug Research: Serves as a core scaffold for developing kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Development: Used in the research and production of nucleotide analogues for treating viral infections.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and biochemical assays.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke molecular synthesis.
• Academic Research: Utilized in university and institutional labs for exploring new chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	1-(2-Hydroxyethyl)-6-Mercapto-1,5-Dihydro-4{H}-Pyrazolo[3,4-{D}]Pyrimidin-4-One
CAS No.	941868-06-0
Molecular Formula	C8H10N4O2S
Molecular Weight	226.26 g/mol
Synonyms	6-Mercapto-1-(2-hydroxyethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1,5-Dihydro-1-(2-hydroxyethyl)-6-mercapto-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Thio-1-(2-hydroxyethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; HEPP Intermediate; Pyrazolopyrimidinone derivative; 941868-06-0; 1-(2-Hydroxyethyl)-6-thioxo-6,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxyethyl)-6-Mercapto-1,5-Dihydro-4{H}-Pyrazolo[3,4-{D}]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with high-grade pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.