Description

2-Chloro-4-Isopropylpyrimidine is a versatile halogenated pyrimidine derivative, a key building block in advanced organic synthesis. Its value lies in its reactive chloro substituent and the steric influence of the isopropyl group, enabling precise molecular construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel pyrimidine-based ligands for catalytic systems in fine chemical manufacturing.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis Building Block: Provides a versatile handle for medicinal and process chemists to introduce the pyrimidine core into complex molecular architectures.

Basic Information

Product Name	2-Chloro-4-Isopropylpyrimidine
CAS No.	941294-36-6
Molecular Formula	C7H9ClN2
Molecular Weight	156.61 g/mol
Synonyms	4-Isopropyl-2-chloropyrimidine; 2-Chloro-4-(1-methylethyl)pyrimidine; 2-Chloro-4-propan-2-ylpyrimidine; Pyrimidine, 2-chloro-4-(1-methylethyl)-; 941294-36-6; 2-Cl-4-iPr-Pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Isopropylpyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.