Description

4-Chloro-6-(4-Methyl-1H-Imidazol-1-Yl)Pyrimidine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry where it serves as a key precursor for kinase inhibitors and other biologically active agents. Pharmaceutical R&D departments, agrochemical manufacturers, and specialty chemical synthesis companies need this material for developing new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of protein kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation herbicides and fungicides.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzymatic pathways and cellular processes.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of client-specific advanced intermediates under cGMP conditions.
• Material Science Research: Investigated as a monomer or ligand for constructing functional organic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-6-(4-Methyl-1H-Imidazol-1-Yl)Pyrimidine
CAS No.	941294-32-2
Molecular Formula	C8H7ClN4
Molecular Weight	194.62 g/mol
Synonyms	4-Chloro-6-(4-methylimidazol-1-yl)pyrimidine; 4-Chloro-6-(4-methyl-1H-imidazol-1-yl)pyrimidine; 941294-32-2; 4-Methyl-1-(6-chloropyrimidin-4-yl)-1H-imidazole; 6-Chloro-4-(4-methyl-1-imidazolyl)pyrimidine; 4-(4-Methyl-1-imidazolyl)-6-chloropyrimidine; 1-(6-Chloro-4-pyrimidinyl)-4-methyl-1H-imidazole
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(4-Methyl-1H-Imidazol-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.