Description

2-Aminomethyl-4-Trifluoromethyl-Phenol is a versatile fluorinated phenolic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an aminomethyl and a trifluoromethyl group on the phenol ring, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for synthesizing fluorinated polymers and specialty resins with unique surface properties and chemical resistance.
• Chemical Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships (SAR).
• Dye and Pigment Intermediate: Used in the production of specialized fluorinated colorants with improved lightfastness and solubility.

Basic Information

Product Name	2-Aminomethyl-4-Trifluoromethyl-Phenol
CAS No.	940875-31-0
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-(Aminomethyl)-4-(trifluoromethyl)phenol; 4-Trifluoromethyl-2-aminomethylphenol; 2-Hydroxy-5-(trifluoromethyl)benzylamine; α-Amino-2-hydroxy-5-(trifluoromethyl)toluene; (2-Hydroxy-5-(trifluoromethyl)phenyl)methanamine; 5-Trifluoromethylsalicylamine; 2-Aminomethyl-α,α,α-trifluoro-p-cresol
EINECS	Contact for details

Quality Control

Our 2-Aminomethyl-4-Trifluoromethyl-Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.