Description

4-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) chemical intermediate with a molecular weight of 326.82, essential for advanced synthetic chemistry. This compound matters as a key building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile piperidine-pyrimidine scaffold. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized fine chemicals.
• Academic & Institutional Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.
• Library Synthesis for High-Throughput Screening: Used to generate diverse compound libraries for biological activity screening in drug discovery campaigns.

Basic Information

Product Name	4-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-79-5
Molecular Formula	C15H23ClN4O2
Molecular Weight	326.82 g/mol
Synonyms	tert-Butyl 4-[[(6-chloropyrimidin-4-yl)amino]methyl]piperidine-1-carboxylate; 1-Boc-4-[(6-chloro-4-pyrimidinylamino)methyl]piperidine; 4-[(6-Chloro-4-pyrimidinylamino)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-chloropyrimidin-4-ylamino)methyl]piperidine; 4-[(6-Chloro-pyrimidin-4-ylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester; 4-((6-Chloropyrimidin-4-ylamino)methyl)piperidine-1-carboxylic acid tert-butyl ester; 4-[(6-Chloro-4-pyrimidinyl)aminomethyl]-1-piperidinecarboxylic acid tert-butyl ester; 4-[(6-Chloro-pyrimidin-4-ylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure a consistent purity of 98+%. Every batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light sources.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.