Description

3-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) chemical intermediate with the molecular formula C15H23ClN4O2 and a molecular weight of 326.82. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

This advanced intermediate is designed for specialized synthetic applications, offering a versatile scaffold for molecular diversification.

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrimidine-piperidine core is relevant.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Serves as a building block for creating molecular probes, tags, or linkers used in studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on laboratory to pilot scale.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploring new chemical spaces in organic and medicinal chemistry.

Basic Information

Item	Details
Product Name	3-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-78-4
Molecular Formula	C15H23ClN4O2
Molecular Weight	326.82 g/mol
Synonyms	1-Boc-3-[(6-chloropyrimidin-4-ylamino)methyl]piperidine; tert-Butyl 3-{[(6-chloropyrimidin-4-yl)amino]methyl}piperidine-1-carboxylate; 3-((6-Chloropyrimidin-4-ylamino)methyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[(6-chloro-4-pyrimidinyl)amino]methyl]piperidine; N-[(1-Boc-3-piperidinyl)methyl]-6-chloro-4-pyrimidinamine; 939986-78-4; Boc-3-(6-chloro-pyrimidin-4-ylaminomethyl)-piperidine
EINECS	Contact for details

Quality Control

Our 3-[(6-Chloro-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified 98+% minimum assay. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.