Description

4-(6-Chloro-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) chemical intermediate with the molecular formula C14H21ClN4O2 and a molecular weight of 312.80. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Organic Synthesis Reagent: Used in coupling reactions and as a protected piperidine derivative for constructing complex heterocyclic compounds.
• Medicinal Chemistry Research: Essential for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Can be utilized to develop tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	4-(6-Chloro-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-76-2
Molecular Formula	C14H21ClN4O2
Molecular Weight	312.80 g/mol
Synonyms	tert-Butyl 4-[(6-chloropyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(6-chloro-4-pyrimidinyl)amino]piperidine; 4-(6-Chloro-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester; 4-[(6-Chloropyrimidin-4-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-chloro-4-pyrimidinyl)amino]piperidine; N-(1-Boc-4-piperidinyl)-6-chloro-4-pyrimidinamine; 939986-76-2
EINECS	Contact for details

Quality Control

Our 4-(6-Chloro-Pyrimidin-4-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the specified 98+% purity grade. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.