Description

3-(6-Chloro-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) chemical intermediate with the molecular formula C15H22ClN3O3 and a molecular weight of 327.81. This compound is a critical building block in modern pharmaceutical synthesis, valued for its piperidine and pyrimidine moieties which are prevalent in active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

This specialized intermediate is designed for advanced synthetic chemistry applications, particularly in regulated industries where purity and consistency are paramount.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and antiviral therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes and enzyme inhibitors in basic research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis organizations (CSOs) and CDMOs producing APIs under cGMP guidelines.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.
• Library Synthesis: Employed in combinatorial chemistry to create diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-(6-Chloro-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-45-5
Molecular Formula	C15H22ClN3O3
Molecular Weight	327.81 g/mol
Synonyms	1-Boc-3-((6-chloropyrimidin-4-yloxy)methyl)piperidine; tert-Butyl 3-((6-chloropyrimidin-4-yloxy)methyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-((6-chloropyrimidin-4-yloxy)methyl)piperidine; 3-((6-Chloro-4-pyrimidinyloxy)methyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 3-[(6-Chloropyrimidin-4-yl)oxymethyl]piperidine-1-carboxylic acid tert-butyl ester; 939986-45-5; Boc-3-(6-chloro-pyrimidin-4-yloxymethyl)-piperidine.
EINECS	Contact for details

Quality Control

Our 3-(6-Chloro-Pyrimidin-4-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the specified purity of 98+% and identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in research and development under quality-by-design (QbD) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.