Description

3-Fluoro-5-Iodophenol is a versatile halogenated phenol derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the development of advanced electronic display materials and organic light-emitting diodes (OLEDs) due to its polarizable iodine atom and molecular geometry.
• Cross-Coupling Reactions: Essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for creating biaryl and complex aromatic structures.
• Chemical Research & Development: Valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating specialized chemical libraries.
• Polymer Modification: Intermediate for synthesizing functional monomers or additives to impart specific properties like flame retardancy or UV stability to polymers.

Basic Information

Item	Details
Product Name	3-Fluoro-5-Iodophenol
CAS No.	939771-60-5
Molecular Formula	C6H4FIO
Molecular Weight	237.99 g/mol
Synonyms	3-Fluoro-5-iodophenol; 5-Iodo-3-fluorophenol; Phenol, 3-fluoro-5-iodo-; 3-F-5-I-Phenol; 939771-60-5; AI3-28635; BRN 2933627; SCHEMBL2180645
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Iodophenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.