Description

2-(Bromomethyl)-5-(Trifluoromethyl)Benzenamine is a versatile aromatic amine building block featuring both bromomethyl and trifluoromethyl functional groups. This compound is critical for the synthesis of complex molecules, offering unique reactivity and physicochemical properties for advanced material and pharmaceutical development. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Incorporated into the design of advanced polymers, liquid crystals, and organic electronic materials to modify electronic properties and solubility.
• Fluorine Chemistry Research: An important substrate for studying nucleophilic substitution reactions and developing new fluorination methodologies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	2-(Bromomethyl)-5-(Trifluoromethyl)Benzenamine
CAS No.	939758-32-4
Molecular Formula	C8H7BrF3N
Molecular Weight	254.05 g/mol
Synonyms	2-(Bromomethyl)-5-(trifluoromethyl)aniline; 2-Amino-5-(trifluoromethyl)benzyl bromide; 5-(Trifluoromethyl)-2-aminobenzyl bromide; α-Bromo-5-(trifluoromethyl)-o-toluidine; 2-Amino-α-bromo-5-(trifluoromethyl)toluene; Benzenamine, 2-(bromomethyl)-5-(trifluoromethyl)-; (2-Amino-5-(trifluoromethyl)phenyl)methanol bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-5-(Trifluoromethyl)Benzenamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.