Description

7-Cyclopropyl-1-Ethyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid CAS NO 938002-51-8 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly those targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used as a scaffold or core structure for designing and optimizing new chemical entities with potential biological activity in high-throughput screening and lead optimization programs.
• Kinase Inhibitor Development: Its dihydropyridopyrimidine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel heterocyclic chemistry.

Basic Information

Product Name	7-Cyclopropyl-1-Ethyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	938002-51-8
Molecular Formula	C14H15N3O3S
Molecular Weight	305.35 g/mol
Synonyms	7-Cyclopropyl-1-ethyl-2-mercapto-4-oxo-1,4-dihydro-5-pyrido[2,3-d]pyrimidinecarboxylic acid; 1,4-Dihydro-7-cyclopropyl-1-ethyl-2-mercapto-4-oxopyrido[2,3-d]pyrimidine-5-carboxylic Acid; 938002-51-8; Pyrido[2,3-d]pyrimidine-5-carboxylic acid derivative; Dihydropyridopyrimidinecarboxylic acid; Ethyl-cyclopropyl-mercapto-oxo-dihydropyridopyrimidinecarboxylic acid; Advanced kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our 7-Cyclopropyl-1-Ethyl-2-Mercapto-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.