Description

Cyclopentanecarboxamide, n-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1-phenyl-3-propyl-5-pyrimidinyl)- is a high-purity, advanced pharmaceutical intermediate with the CAS number 937804-85-8. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs due to its functionalized pyrimidinone core.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects requiring high chemical purity and reliable documentation.
• Academic Research: Utilized in university and institutional labs for investigating new organic reactions and heterocyclic compound libraries.
• Reference Standard: Can be supplied as a characterized standard for analytical method development and quality control in API production.

Basic Information

Product Name	Cyclopentanecarboxamide, n-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1-phenyl-3-propyl-5-pyrimidinyl)-
CAS No.	937804-85-8
Molecular Formula	C19H24N4O3
Molecular Weight	356.42 g/mol
Synonyms	1-Phenyl-3-propyl-6-amino-5-(cyclopentanecarboxamido)-1,2,3,4-tetrahydro-2,4-pyrimidinedione; 5-[(Cyclopentanecarbonyl)amino]-1,2,3,4-tetrahydro-2,4-dioxo-1-phenyl-3-propyl-6-pyrimidinamine; 6-Amino-5-(cyclopentanecarboxamido)-1-phenyl-3-propyl-1,2,3,4-tetrahydro-2,4-pyrimidinedione; N-(6-Amino-2,4-dioxo-1-phenyl-3-propyl-1,2,3,4-tetrahydro-5-pyrimidinyl)cyclopentanecarboxamide; Cyclopentanecarboxylic acid [6-amino-2,4-dioxo-1-phenyl-3-propyl-1,2,3,4-tetrahydro-5-pyrimidinyl]amide
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxamide, n-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1-phenyl-3-propyl-5-pyrimidinyl)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure full traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.