Description

2-(3-Fluoro-Benzylamino)-Ethanol is a versatile fluorinated amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. Industries that require it include pharmaceutical R&D, agrochemical manufacturing, and fine chemical production, where its unique structure enables the introduction of both fluorine and ethanolamine functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating chiral ligands and metal-organic catalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty surfactants, corrosion inhibitors, and other performance chemicals.
• Bioconjugation and Linker Chemistry: The amino and hydroxyl groups make it suitable for creating chemical linkers in bioconjugation and prodrug strategies.
• Material Science Research: Investigated as a monomer or modifier in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	2-(3-Fluoro-Benzylamino)-Ethanol
CAS No.	937688-47-6
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	2-[(3-Fluorophenyl)methylamino]ethanol; N-(3-Fluorobenzyl)ethanolamine; 2-[(3-Fluorobenzyl)amino]ethan-1-ol; Ethanol, 2-[(3-fluorophenyl)methylamino]-; 3-Fluoro-N-(2-hydroxyethyl)benzylamine; 2-(3-Fluorobenzylamino)ethanol; N-(2-Hydroxyethyl)-3-fluorobenzylamine; 3-Fluorobenzylethanolamine
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-Benzylamino)-Ethanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.