Description

4-(2,2-Difluoroethoxy)Aniline is a specialized aniline derivative featuring a difluoroethoxy substituent, making it a valuable fluorinated building block in advanced organic synthesis. This compound matters for its role in introducing fluorine-containing motifs, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated components for advanced display technologies.
• Polymer Modification: Employed to introduce fluorine-containing aniline units into polymers, improving their chemical resistance and surface properties.
• Organic Electronics: Acts as a starting material for synthesizing charge-transport materials or emissive layers in OLED devices.
• Chemical Research: A versatile reagent for academic and industrial research exploring new fluorination strategies and heterocyclic chemistry.

Basic Information

Product Name	4-(2,2-Difluoroethoxy)Aniline
CAS No.	937606-77-4
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	4-(2,2-Difluoroethoxy)benzenamine; 1-Amino-4-(2,2-difluoroethoxy)benzene; p-(2,2-Difluoroethoxy)aniline; Benzenamine, 4-(2,2-difluoroethoxy)-; 4-Amino-1-(2,2-difluoroethoxy)benzene; Aniline, 4-(2,2-difluoroethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-(2,2-Difluoroethoxy)Aniline is produced under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.