Description

3-(4-Bromobenzyl)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-Ol is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS registry number 937604-16-5. This heterocyclic compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing targeted therapies for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a molecular scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and biological pathways.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-(4-Bromobenzyl)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-Ol
CAS No.	937604-16-5
Molecular Formula	C₁₁H₈BrN₅O
Molecular Weight	306.12 g/mol
Synonyms	3-[(4-Bromophenyl)methyl]-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol; 3-(4-Bromobenzyl)-7-hydroxy-[1,2,3]triazolo[4,5-d]pyrimidine; 7-Hydroxy-3-(4-bromobenzyl)-[1,2,3]triazolo[4,5-d]pyrimidine; 3-(p-Bromobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol; 937604-16-5; BBT-7-ol; [1,2,3]Triazolo[4,5-d]pyrimidin-7-ol, 3-[(4-bromophenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 3-(4-Bromobenzyl)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.