Description

[2-Amino-7,8-Dihydropyrido[4,3-D]Pyrimidin-6(5H)-Yl](Phenyl)Methanone is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for oncology and inflammatory diseases.
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing potent and selective kinase inhibitors due to its privileged pyridopyrimidine architecture.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Biochemical Tool Compound: Employed in biochemical assays and high-throughput screening to study enzyme function and identify new therapeutic targets.
• Custom Synthesis & Contract Manufacturing: Supplied for custom chemical synthesis projects requiring high-fidelity, complex heterocyclic building blocks.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	[2-Amino-7,8-Dihydropyrido[4,3-D]Pyrimidin-6(5H)-Yl](Phenyl)Methanone
CAS No.	937604-00-7
Molecular Formula	C₁₄H₁₄N₄O
Molecular Weight	254.29 g/mol
Synonyms	2-Amino-5,6,7,8-tetrahydro-6-(benzoyl)pyrido[4,3-d]pyrimidine; (2-Amino-5,6,7,8-tetrahydro-6H-pyrido[4,3-d]pyrimidin-6-yl)(phenyl)methanone; Phenyl(2-amino-5,6,7,8-tetrahydro-6H-pyrido[4,3-d]pyrimidin-6-yl)methanone; 6-Benzoyl-2-amino-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; CAS 937604-00-7
EINECS	Contact for details

Quality Control

Our [2-Amino-7,8-Dihydropyrido[4,3-D]Pyrimidin-6(5H)-Yl](Phenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.