Description

Ethyl [(4-Thien-2-Ylpyrimidin-2-Yl)Thio]Acetate is a high-value, sulfur-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thioether-linked pyrimidine-thiophene scaffold is crucial. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of advanced organic electronic materials or specialty polymers.
• Chemical Biology Probe Synthesis: Employed to create molecular tools and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	Ethyl [(4-Thien-2-Ylpyrimidin-2-Yl)Thio]Acetate
CAS No.	937599-90-1
Molecular Formula	C12H12N2O2S2
Molecular Weight	280.37 g/mol
Synonyms	Ethyl 2-[(4-(thiophen-2-yl)pyrimidin-2-yl)sulfanyl]acetate; 2-[(4-(Thiophen-2-yl)pyrimidin-2-yl)thio]acetic acid ethyl ester; Ethyl (4-(thiophen-2-yl)pyrimidin-2-ylthio)acetate; 937599-90-1; SCHEMBL218055; AKOS040759246; ZINC000003930756; Ethyl [(4-(2-thienyl)-2-pyrimidinyl)thio]acetate
EINECS	Contact for details

Quality Control

Our Ethyl [(4-Thien-2-Ylpyrimidin-2-Yl)Thio]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive (store away from light), and prolonged exposure to air should be minimized.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.