Description

2-Mercapto-1-(2-Methoxyethyl)-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused pyridopyrimidine structure. This compound is of significant value for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• Oncology Drug Development: A key scaffold for creating potential kinase inhibitors and other targeted cancer therapies due to its pyridopyrimidine core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Development: The carboxylic acid and mercapto functional groups allow for derivatization, making it suitable for creating chemical probes or conjugates for biological studies.

Basic Information

Product Name	2-Mercapto-1-(2-Methoxyethyl)-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	937599-80-9
Molecular Formula	C13H15N3O4S
Molecular Weight	309.34 g/mol
Synonyms	7-Methyl-2-mercapto-1-(2-methoxyethyl)-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylic acid; 1,4-Dihydro-7-methyl-2-mercapto-1-(2-methoxyethyl)-4-oxopyrido[2,3-d]pyrimidine-5-carboxylic Acid; Pyrido[2,3-d]pyrimidine-5-carboxylic acid, 1,4-dihydro-7-methyl-2-mercapto-1-(2-methoxyethyl)-4-oxo-; CAS 937599-80-9; 937599-80-9
EINECS	Contact for details

Quality Control

Our 2-Mercapto-1-(2-Methoxyethyl)-7-Methyl-4-Oxo-1,4-Dihydropyrido[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.